Cancer Center Member Publications and Abstracts Site

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Academic TitleProfessor
DepartmentNeurology; Feinberg School of Medicine
AffiliationsCancer Cell Biology (Member)
CampusChicago
AddressABBOTT 710 N Lake Shore Dr 13-715 CH O402
Telephone+1 312 503 4737
Fax+1 312 908 0865
Email
PubMed IDs
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Publications (19)

Publications
Ajroud-Driss, S.; Fecto, F.; Ajroud, K.; Lalani, I.; Calvo, S. E.; Mootha, V. K.; Deng, H. X.; Siddique, N.; Tahmoush, A. J.; Heiman-Patterson, T. D.; Siddique, T. Mutation in the novel nuclear-encoded mitochondrial protein CHCHD10 in a family with autosomal dominant mitochondrial myopathy.Neurogenetics (2015) 16:1-9. 25193783; 10.1007/s10048-014-0421-1
Ajroud-Driss, S.; Siddique, T. Sporadic and Hereditary Amyotrophic Lateral Sclerosis (ALS).Biochim Biophys Acta (2015) 1852:679-684. 25193032; 10.1016/j.bbadis.2014.08.010
Arrat, H.; Lukas, T. J.; Siddique, T. ACTH (Acthar Gel) Reduces Toxic SOD1 Protein Linked to Amyotrophic Lateral Sclerosis in Transgenic Mice: A Novel Observation.PLoS One (2015) 10:e0125638. 25955410; 10.1371/journal.pone.0125638
Fecto, F.; Esengul, Y. T.; Siddique, T. Protein recycling pathways in neurodegenerative diseases.Alzheimers Res Ther (2014) 6:13. 25031631; PMC4055009; 10.1186/alzrt243
Gallardo, G.; Barowski, J.; Ravits, J.; Siddique, T.; Lingrel, J. B.; Robertson, J.; Steen, H.; Bonni, A. An alpha2-Na/K ATPase/alpha-adducin complex in astrocytes triggers non-cell autonomous neurodegeneration.Nat Neurosci (2014) 17:1710-1719. 25344630; 10.1038/nn.3853
Gorrie, G. H.; Fecto, F.; Radzicki, D.; Weiss, C.; Shi, Y.; Dong, H.; Zhai, H.; Fu, R.; Liu, E.; Li, S.; Arrat, H.; Bigio, E. H.; Disterhoft, J. F.; Martina, M.; Mugnaini, E.; Siddique, T.; Deng, H. X. Dendritic spinopathy in transgenic mice expressing ALS/dementia-linked mutant UBQLN2.Proc Natl Acad Sci U S A (2014) 111:14524-14529. 25246588; PMC4209984; 10.1073/pnas.1405741111
Koschnitzky, J. E.; Quinlan, K. A.; Lukas, T. J.; Kajtaz, E.; Kocevar, E. J.; Mayers, W. F.; Siddique, T.; Heckman, C. J. The effect of fluoxetine on disease progression in a mouse model of ALS.J Neurophysiol (2014) In process. 24598527; 10.1152/jn.00425.2013
Lukas, T. J.; Schiltz, G. E.; Arrat, H.; Scheidt, K.; Siddique, T. Discovery of 1,3,4-oxidiazole scaffold compounds as inhibitors of superoxide dismutase expression.Bioorg Med Chem Lett (2014) 24:1532-1537. 24560539; 10.1016/j.bmcl.2014.01.078
Wang, X.; Blanchard, J.; Grundke-Iqbal, I.; Wegiel, J.; Deng, H. X.; Siddique, T.; Iqbal, K. Alzheimer disease and amyotrophic lateral sclerosis: an etiopathogenic connection.Acta Neuropathol (2014) 127:243-256. 24136402; PMC3947003; 10.1007/s00401-013-1175-9
Al-Chalabi, A.; Kwak, S.; Mehler, M.; Rouleau, G.; Siddique, T.; Strong, M.; Leigh, P. N. Genetic and epigenetic studies of amyotrophic lateral sclerosis.Amyotroph Lateral Scler Frontotemporal Degener (2013) 14 Suppl 1:44-52. 23678879; 10.3109/21678421.2013.778571
Allen, J. A.; Chen, R.; Ajroud-Driss, S.; Sufit, R. L.; Heller, S.; Siddique, T.; Wolfe, L. Gastrostomy tube placement by endoscopy versus radiologic methods in patients with ALS: a retrospective study of complications and outcome.Amyotroph Lateral Scler Frontotemporal Degener (2013) 14:308-314. 23286755; 10.3109/21678421.2012.751613
Bigio, E. H.; Wu, J. Y.; Deng, H. X.; Bit-Ivan, E. N.; Mao, Q.; Ganti, R.; Peterson, M.; Siddique, N.; Geula, C.; Siddique, T.; Mesulam, M. Inclusions in frontotemporal lobar degeneration with TDP-43 proteinopathy (FTLD-TDP) and amyotrophic lateral sclerosis (ALS), but not FTLD with FUS proteinopathy (FTLD-FUS), have properties of amyloid.Acta Neuropathol (2013) 125:463-465. 23378033; PMC3593646; 10.1007/s00401-013-1089-6
Rivera, I.; Ajroud-Driss, S.; Casey, P.; Heller, S.; Allen, J.; Siddique, T.; Sufit, R. Prevalence and characteristics of pain in early and late stages of ALS.Amyotroph Lateral Scler Frontotemporal Degener (2013) 14:369-372. 23286754; 10.3109/21678421.2012.751614
Mishra, M.; Paunesku, T.; Woloschak, G. E.; Siddique, T.; Zhu, L. J.; Lin, S.; Greco, K.; Bigio, E. H. Gene expression analysis of frontotemporal lobar degeneration of the motor neuron disease type with ubiquitinated inclusions.Acta Neuropathol (2007) 114:81-94. 17569064; 10.1007/s00401-007-0240-7
Deng, H. X.; Shi, Y.; Furukawa, Y.; Zhai, H.; Fu, R.; Liu, E.; Gorrie, G. H.; Khan, M. S.; Hung, W. Y.; Bigio, E. H.; Lukas, T.; Dal Canto, M. C.; O'Halloran, T. V.; Siddique, T. Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria.Proc Natl Acad Sci U S A (2006) 103:7142-7147. 16636275; PMC1447523; 10.1073/pnas.0602046103
Furukawa, Y.; Fu, R.; Deng, H. X.; Siddique, T.; O'Halloran, T. V. Disulfide cross-linked protein represents a significant fraction of ALS-associated Cu, Zn-superoxide dismutase aggregates in spinal cords of model mice.Proc Natl Acad Sci U S A (2006) 103:7148-7153. 16636274; PMC1447524; 10.1073/pnas.0602048103
Li, X.; Rowland, L. P.; Mitsumoto, H.; Przedborski, S.; Bird, T. D.; Schellenberg, G. D.; Peskind, E.; Johnson, N.; Siddique, T.; Mesulam, M. M.; Weintraub, S.; Mastrianni, J. A. Prion protein codon 129 genotype prevalence is altered in primary progressive aphasia.Ann Neurol (2005) 58:858-864. 16315279; 10.1002/ana.20646
Bigio, E. H.; Johnson, N. A.; Rademaker, A. W.; Fung, B. B.; Mesulam, M. M.; Siddique, N.; Dellefave, L.; Caliendo, J.; Freeman, S.; Siddique, T. Neuronal ubiquitinated intranuclear inclusions in familial and non-familial frontotemporal dementia of the motor neuron disease type associated with amyotrophic lateral sclerosis.J Neuropathol Exp Neurol (2004) 63:801-811. 15330335
Deng, H. X.; Tainer, J. A.; Mitsumoto, H.; Ohnishi, A.; He, X.; Hung, W. Y.; Zhao, Y.; Juneja, T.; Hentati, A.; Siddique, T. Two novel SOD1 mutations in patients with familial amyotrophic lateral sclerosis.Hum Mol Genet (1995) 4:1113-1116. 7655471

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Last updated from PubMed on Friday, May 22, 2015