Cancer Center Member Publications and Abstracts Site

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Academic TitleProfessor
DepartmentNeurology; Feinberg School of Medicine
AffiliationsCancer Cell Biology (Member)
AddressABBOTT 710 N Lake Shore Dr 13-715 CH O402
Telephone+1 312 503 4737
Fax+1 312 908 0865
PubMed IDs
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Publications (19)

Ajroud-Driss, S.; Fecto, F.; Ajroud, K.; Lalani, I.; Calvo, S. E.; Mootha, V. K.; Deng, H. X.; Siddique, N.; Tahmoush, A. J.; Heiman-Patterson, T. D.; Siddique, T. Mutation in the novel nuclear-encoded mitochondrial protein CHCHD10 in a family with autosomal dominant mitochondrial myopathy.Neurogenetics (2015) 16:1-9. 25193783; 10.1007/s10048-014-0421-1
Ajroud-Driss, S.; Siddique, T. Sporadic and Hereditary Amyotrophic Lateral Sclerosis (ALS).Biochim Biophys Acta (2015) 1852:679-684. 25193032; 10.1016/j.bbadis.2014.08.010
Arrat, H.; Lukas, T. J.; Siddique, T. ACTH (Acthar Gel) Reduces Toxic SOD1 Protein Linked to Amyotrophic Lateral Sclerosis in Transgenic Mice: A Novel Observation.PLoS One (2015) 10:e0125638. 25955410; 10.1371/journal.pone.0125638
Fecto, F.; Esengul, Y. T.; Siddique, T. Protein recycling pathways in neurodegenerative diseases.Alzheimers Res Ther (2014) 6:13. 25031631; PMC4055009; 10.1186/alzrt243
Gallardo, G.; Barowski, J.; Ravits, J.; Siddique, T.; Lingrel, J. B.; Robertson, J.; Steen, H.; Bonni, A. An alpha2-Na/K ATPase/alpha-adducin complex in astrocytes triggers non-cell autonomous neurodegeneration.Nat Neurosci (2014) 17:1710-1719. 25344630; 10.1038/nn.3853
Gorrie, G. H.; Fecto, F.; Radzicki, D.; Weiss, C.; Shi, Y.; Dong, H.; Zhai, H.; Fu, R.; Liu, E.; Li, S.; Arrat, H.; Bigio, E. H.; Disterhoft, J. F.; Martina, M.; Mugnaini, E.; Siddique, T.; Deng, H. X. Dendritic spinopathy in transgenic mice expressing ALS/dementia-linked mutant UBQLN2.Proc Natl Acad Sci U S A (2014) 111:14524-14529. 25246588; PMC4209984; 10.1073/pnas.1405741111
Koschnitzky, J. E.; Quinlan, K. A.; Lukas, T. J.; Kajtaz, E.; Kocevar, E. J.; Mayers, W. F.; Siddique, T.; Heckman, C. J. The effect of fluoxetine on disease progression in a mouse model of ALS.J Neurophysiol (2014) In process. 24598527; 10.1152/jn.00425.2013
Lukas, T. J.; Schiltz, G. E.; Arrat, H.; Scheidt, K.; Siddique, T. Discovery of 1,3,4-oxidiazole scaffold compounds as inhibitors of superoxide dismutase expression.Bioorg Med Chem Lett (2014) 24:1532-1537. 24560539; 10.1016/j.bmcl.2014.01.078
Wang, X.; Blanchard, J.; Grundke-Iqbal, I.; Wegiel, J.; Deng, H. X.; Siddique, T.; Iqbal, K. Alzheimer disease and amyotrophic lateral sclerosis: an etiopathogenic connection.Acta Neuropathol (2014) 127:243-256. 24136402; PMC3947003; 10.1007/s00401-013-1175-9
Al-Chalabi, A.; Kwak, S.; Mehler, M.; Rouleau, G.; Siddique, T.; Strong, M.; Leigh, P. N. Genetic and epigenetic studies of amyotrophic lateral sclerosis.Amyotroph Lateral Scler Frontotemporal Degener (2013) 14 Suppl 1:44-52. 23678879; 10.3109/21678421.2013.778571
Allen, J. A.; Chen, R.; Ajroud-Driss, S.; Sufit, R. L.; Heller, S.; Siddique, T.; Wolfe, L. Gastrostomy tube placement by endoscopy versus radiologic methods in patients with ALS: a retrospective study of complications and outcome.Amyotroph Lateral Scler Frontotemporal Degener (2013) 14:308-314. 23286755; 10.3109/21678421.2012.751613
Bigio, E. H.; Wu, J. Y.; Deng, H. X.; Bit-Ivan, E. N.; Mao, Q.; Ganti, R.; Peterson, M.; Siddique, N.; Geula, C.; Siddique, T.; Mesulam, M. Inclusions in frontotemporal lobar degeneration with TDP-43 proteinopathy (FTLD-TDP) and amyotrophic lateral sclerosis (ALS), but not FTLD with FUS proteinopathy (FTLD-FUS), have properties of amyloid.Acta Neuropathol (2013) 125:463-465. 23378033; PMC3593646; 10.1007/s00401-013-1089-6
Rivera, I.; Ajroud-Driss, S.; Casey, P.; Heller, S.; Allen, J.; Siddique, T.; Sufit, R. Prevalence and characteristics of pain in early and late stages of ALS.Amyotroph Lateral Scler Frontotemporal Degener (2013) 14:369-372. 23286754; 10.3109/21678421.2012.751614
Mishra, M.; Paunesku, T.; Woloschak, G. E.; Siddique, T.; Zhu, L. J.; Lin, S.; Greco, K.; Bigio, E. H. Gene expression analysis of frontotemporal lobar degeneration of the motor neuron disease type with ubiquitinated inclusions.Acta Neuropathol (2007) 114:81-94. 17569064; 10.1007/s00401-007-0240-7
Deng, H. X.; Shi, Y.; Furukawa, Y.; Zhai, H.; Fu, R.; Liu, E.; Gorrie, G. H.; Khan, M. S.; Hung, W. Y.; Bigio, E. H.; Lukas, T.; Dal Canto, M. C.; O'Halloran, T. V.; Siddique, T. Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria.Proc Natl Acad Sci U S A (2006) 103:7142-7147. 16636275; PMC1447523; 10.1073/pnas.0602046103
Furukawa, Y.; Fu, R.; Deng, H. X.; Siddique, T.; O'Halloran, T. V. Disulfide cross-linked protein represents a significant fraction of ALS-associated Cu, Zn-superoxide dismutase aggregates in spinal cords of model mice.Proc Natl Acad Sci U S A (2006) 103:7148-7153. 16636274; PMC1447524; 10.1073/pnas.0602048103
Li, X.; Rowland, L. P.; Mitsumoto, H.; Przedborski, S.; Bird, T. D.; Schellenberg, G. D.; Peskind, E.; Johnson, N.; Siddique, T.; Mesulam, M. M.; Weintraub, S.; Mastrianni, J. A. Prion protein codon 129 genotype prevalence is altered in primary progressive aphasia.Ann Neurol (2005) 58:858-864. 16315279; 10.1002/ana.20646
Bigio, E. H.; Johnson, N. A.; Rademaker, A. W.; Fung, B. B.; Mesulam, M. M.; Siddique, N.; Dellefave, L.; Caliendo, J.; Freeman, S.; Siddique, T. Neuronal ubiquitinated intranuclear inclusions in familial and non-familial frontotemporal dementia of the motor neuron disease type associated with amyotrophic lateral sclerosis.J Neuropathol Exp Neurol (2004) 63:801-811. 15330335
Deng, H. X.; Tainer, J. A.; Mitsumoto, H.; Ohnishi, A.; He, X.; Hung, W. Y.; Zhao, Y.; Juneja, T.; Hentati, A.; Siddique, T. Two novel SOD1 mutations in patients with familial amyotrophic lateral sclerosis.Hum Mol Genet (1995) 4:1113-1116. 7655471

The above publications are sorted by year, faculty last name, and first author. Click on any highlighted author listed to find all publications attributed to that individual. Click on the publication title to see the abstract. First authors who are faculty are highlighted like this. Last authors who are faculty are highlighted like this. Other authors who are faculty are highlighted like this.

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Last updated from PubMed on Friday, May 22, 2015