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Elizabeth J Perlman, MDEdit profile     Publications     Word cloud      
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Academic TitleProfessor
DepartmentPathology; Feinberg School of Medicine
AffiliationsTranslational Research in Solid Tumors (Member)
CampusChicago
AddressWARD 303 E Chicago Ave 3-140 CH W127
Email
DescriptionDr. Elizabeth Perlman is a clinician scientist whose predominant clinical role is to serve as the central pathology reviewer for the Children’s Oncology Group Renal Tumor Committee. In this capacity she reviews all pediatric renal tumors registered on COG protocols in the United States. In connection with this role, her laboratory research focuses on the large-scale gene expression, copy number, and sequencing analysis of pediatric renal tumors. The overall goals of these studies are to identify diagnostic classifiers, predictors of relapse, and potential therapeutic targets.
InterestsPediatric renal tumors, Wilms tumors, clear cell sarcoma of kidney, rhabdoid tumor, congenital mesoblastic nephroma
PubMed IDs
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Publications (187)

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Publications
Walz, A. L.; Ooms, A.; Gadd, S.; Gerhard, D. S.; Smith, M. A.; Guidry Auvil, J. M.; Meerzaman, D.; Chen, Q. R.; Hsu, C. H.; Yan, C.; Nguyen, C.; Hu, Y.; Bowlby, R.; Brooks, D.; Ma, Y.; Mungall, A. J.; Moore, R. A.; Schein, J.; Marra, M. A.; Huff, V.; Dome, J. S.; Chi, Y. Y.; Mullighan, C. G.; Ma, J.; Wheeler, D. A.; Hampton, O. A.; Jafari, N.; Ross, N.; Gastier-Foster, J. M.; Perlman, E. J. Recurrent DGCR8, DROSHA, and SIX Homeodomain Mutations in Favorable Histology Wilms Tumors.Cancer Cell (2015) 27:286-297. 25670082; 10.1016/j.ccell.2015.01.003
Dome, J. S.; Perlman, E. J.; Graf, N. Risk stratification for wilms tumor: current approach and future directions.Am Soc Clin Oncol Educ Book (2014) :215-223. 24857079; 10.14694/EdBook_AM.2014.34.215
Doros, L. A.; Rossi, C. T.; Yang, J.; Field, A.; Williams, G. M.; Messinger, Y.; Cajaiba, M. M.; Perlman, E. J.; A Schultz, K.; Cathro, H. P.; Legallo, R. D.; Lafortune, K. A.; Chikwava, K. R.; Faria, P.; Geller, J. I.; Dome, J. S.; Mullen, E. A.; Gratias, E. J.; Dehner, L. P.; Hill, D. A. DICER1 mutations in childhood cystic nephroma and its relationship to DICER1-renal sarcoma.Mod Pathol (2014) 27:1267-1280. 24481001; PMC4117822; 10.1038/modpathol.2013.242
Green, D. M.; Breslow, N. E.; D'Angio, G. J.; Malogolowkin, M. H.; Ritchey, M. L.; Evans, A. E.; Beckwith, J. B.; Perlman, E. J.; Shamberger, R. C.; Peterson, S.; Grundy, P. E.; Dome, J. S.; Thomas, P. R.; Kalapurakal, J. A. Outcome of patients with stage II/favorable histology wilms tumor with and without local tumor spill: A report from the National Wilms Tumor Study Group.Pediatr Blood Cancer (2014) 61:134-139. 24038736; PMC3933291; 10.1002/pbc.24658
Reindel, R.; Bischof, J.; Kim, K. Y.; Orenstein, J. M.; Soares, M. B.; Baker, S. C.; Shulman, S. T.; Perlman, E. J.; Lingen, M. W.; Pink, A. J.; Trevenen, C.; Rowley, A. H. CD84 is Markedly Upregulated in Kawasaki Disease Arteriopathy.Clin Exp Immunol (2014) In process. 24635044; 10.1111/cei.12327
Reindel, R.; Kim, K. Y.; Baker, S. C.; Shulman, S. T.; Perlman, E. J.; Lingen, M. W.; Trevenen, C.; Rowley, A. H. Periostin is Upregulated in Coronary Arteriopathy in Kawasaki Disease and is a Potential Diagnostic Biomarker.Pediatr Infect Dis J (2014) 33:659-661. 24476956; PMC4086943; 10.1097/INF.0000000000000233
Stricker, T. P.; Morales La Madrid, A.; Chlenski, A.; Guerrero, L.; Salwen, H. R.; Gosiengfiao, Y.; Perlman, E. J.; Furman, W.; Bahrami, A.; Shohet, J. M.; Zage, P. E.; Hicks, M. J.; Shimada, H.; Suganuma, R.; Park, J. R.; So, S.; London, W. B.; Pytel, P.; Maclean, K. H.; Cohn, S. L. Validation of a prognostic multi-gene signature in high-risk neuroblastoma using the high throughput digital NanoString nCounter system.Mol Oncol (2014) 8:669-678. 24560446; PMC4004665; 10.1016/j.molonc.2014.01.010
Dome, J. S.; Fernandez, C. V.; Mullen, E. A.; Kalapurakal, J. A.; Geller, J. I.; Huff, V.; Gratias, E. J.; Dix, D. B.; Ehrlich, P. F.; Khanna, G.; Malogolowkin, M. H.; Anderson, J. R.; Naranjo, A.; Perlman, E. J. Children's Oncology Group's 2013 blueprint for research: Renal tumors.Pediatr Blood Cancer (2013) 60:994-1000. 23255438; 10.1002/pbc.24419
Ehrlich, P. F.; Anderson, J. R.; Ritchey, M. L.; Dome, J. S.; Green, D. M.; Grundy, P. E.; Perlman, E. J.; Kalapurakal, J. A.; Breslow, N. E.; Shamberger, R. C. Clinicopathologic Findings Predictive of Relapse in Children With Stage III Favorable-Histology Wilms Tumor.J Clin Oncol (2013) 31:1196-1201. 23382471; PMC3595426; 10.1200/JCO.2011.41.1165
Gratias, E. J.; Jennings, L. J.; Anderson, J. R.; Dome, J. S.; Grundy, P.; Perlman, E. J. Gain of 1q is associated with inferior event-free and overall survival in patients with favorable histology wilms tumor: A report from the children's oncology group.Cancer (2013) 119:3887-3894. 23983061; 10.1002/cncr.28239
Kalapurakal, J. A.; Perlman, E. J.; Seibel, N. L.; Ritchey, M.; Dome, J. S.; Grundy, P. E. Outcomes of Patients With Revised Stage I Clear Cell Sarcoma of Kidney Treated in National Wilms Tumor Studies 1-5.Int J Radiat Oncol Biol Phys (2013) 85:428-431. 22658515; 10.1016/j.ijrobp.2012.04.023
Khanna, G.; Naranjo, A.; Hoffer, F.; Mullen, E.; Geller, J.; Gratias, E. J.; Ehrlich, P. F.; Perlman, E. J.; Rosen, N.; Grundy, P.; Dome, J. S. Detection of Preoperative Wilms Tumor Rupture with CT: A Report from the Children's Oncology Group.Radiology (2013) 266:610-617. 23192775; PMC3558872; 10.1148/radiol.12120670
Kieran, K.; Anderson, J. R.; Dome, J. S.; Ehrlich, P. F.; Ritchey, M. L.; Shamberger, R. C.; Perlman, E. J.; Green, D. M.; Davidoff, A. M. Is adrenalectomy necessary during unilateral nephrectomy for Wilms Tumor? A report from the Children's Oncology Group.J Pediatr Surg (2013) 48:1598-1603. 23895979; 10.1016/j.jpedsurg.2013.04.019
Reindel, R.; Baker, S. C.; Kim, K. Y.; Rowley, C. A.; Shulman, S. T.; Orenstein, J. M.; Perlman, E. J.; Lingen, M. W.; Rowley, A. H. Integrins alpha4 and alphaM, collagen1A1, and matrix metalloproteinase 7 are upregulated in acute Kawasaki disease vasculopathy.Pediatr Res (2013) 73:332-336. 23344661; PMC3595104; 10.1038/pr.2012.185
Gadd, S.; Beezhold, P.; Jennings, L.; George, D.; Leuer, K.; Huang, C. C.; Huff, V.; Tognon, C.; Sorensen, P. H.; Triche, T.; Coffin, C. M.; Perlman, E. J. Mediators of Receptor Tyrosine Kinase activation in infantile fibrosarcoma: a Children's Oncology Group study.J Pathol (2012) 228:119-130. 22374738; 10.1002/path.4010
Gadd, S.; Huff, V.; Huang, C. C.; Ruteshouser, E. C.; Dome, J. S.; Grundy, P. E.; Breslow, N.; Jennings, L.; Green, D. M.; Beckwith, J. B.; Perlman, E. J. Clinically Relevant Subsets Identified by Gene Expression Patterns Support a Revised Ontogenic Model of Wilms Tumor: A Children's Oncology Group Study.Neoplasia (2012) 14:742-756. 22952427; PMC3431181
Haskins, W. E.; Eedala, S.; Avinash Jadhav, Y. L.; Labhan, M. S.; Pericherla, V. C.; Perlman, E. J. Insights on neoplastic stem cells from gel-based proteomics of childhood germ cell tumors.Pediatr Blood Cancer (2012) 58:722-728. 21793190; PMC3204330; 10.1002/pbc.23282
Khanna, G.; Rosen, N.; Anderson, J. R.; Ehrlich, P. F.; Dome, J. S.; Gow, K. W.; Perlman, E.; Barnhart, D.; Karolczuk, K.; Grundy, P. Evaluation of diagnostic performance of CT for detection of tumor thrombus in children with Wilms tumor: a report from the Children's Oncology Group.Pediatr Blood Cancer (2012) 58:551-555. 21674767; PMC3175263; 10.1002/pbc.23222
Kieran, K.; Anderson, J. R.; Dome, J. S.; Ehrlich, P. F.; Ritchey, M. L.; Shamberger, R. C.; Perlman, E. J.; Green, D. M.; Davidoff, A. M. Lymph node involvement in Wilms tumor: results from National Wilms Tumor Studies 4 and 5.J Pediatr Surg (2012) 47:700-706. 22498384; 10.1016/j.jpedsurg.2011.08.017
Orenstein, J. M.; Shulman, S. T.; Fox, L. M.; Baker, S. C.; Takahashi, M.; Bhatti, T. R.; Russo, P. A.; Mierau, G. W.; de Chadarevian, J. P.; Perlman, E. J.; Trevenen, C.; Rotta, A. T.; Kalelkar, M. B.; Rowley, A. H. Three linked vasculopathic processes characterize kawasaki disease: a light and transmission electron microscopic study.PLoS One (2012) 7:e38998. 22723916; PMC3377625; 10.1371/journal.pone.0038998

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Last updated from PubMed on Wednesday, May 06, 2015